No; unfortunately, it is not trivial to support this, because the last endpoint sends the reply - we'd have to restructure the chain handler so that the last endpoint returns the reply to it rather than sending it directly. That way, we could advise the chain of handlers, but do the final send outside of the advice.
You are correct that there is not currently an open 'Improvement' JIRA issue for this; feel free to open one.
Gary P. Russell
Spring Integration Team
SpringSource, a division of VMware